How long does stem cell therapy for Primary Immunodeficiency last?
Successful HSCT may provide durable donor-derived immune function in selected disorders, but engraftment and immune recovery must be monitored. This evidence does not imply durable benefit from MSCs, exosomes or a non-haematopoietic infusion.
How stem cells are studied for Primary Immunodeficiency
Primary immunodeficiencies, also called inborn errors of immunity, comprise many genetic disorders with different infection, inflammatory, autoimmune and malignancy risks. Haematopoietic stem-cell transplantation (HSCT) can be established or potentially curative for selected severe diagnoses because it replaces the blood-forming immune system. This is not equivalent to an MSC infusion marketed for general immune support.
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