Multiple sclerosis arises from immune-mediated attack on myelin and oligodendrocytes in the central nervous system, causing demyelination and axonal loss.
Multiple sclerosis arises from immune-mediated attack on myelin and oligodendrocytes in the central nervous system, causing demyelination and axonal loss. Stem-cell strategies target both immune dysregulation and repair: placental mesenchymal stem cells are studied for their capacity to calm autoreactive immune cells and secrete neuroprotective factors, while neurogenic cells are explored for remyelination and axonal support. Preclinical work suggests stem cells migrate toward lesions and release anti-inflammatory mediators. Trials have enrolled relapsing-remitting and progressive forms, but the mechanism of any benefit is incompletely characterised, and no approach yet reverses established disability or halts long-term progression in humans.
| 指示性成本 · 保加利亚 (EU) | €3,000–€8,000 |
|---|---|
| 全球市场成本范围 | €4,140–€92,000 (getlabtest.com, cellmedicine.com) |
| 研究的主要细胞类型 | MSCs from Amniotic Membrane, Neurogenic Cells |
| 批准状态 | 研究性 |
| 注册的临床试验 (ClinicalTrials.gov) | 92 · 14 recruiting now |
For the clinic's own description, see how Stem Plus describes its Multiple Sclerosis programme ↗.
Ninety-two registered trials and 14 recruiting studies investigate stem-cell therapy in MS, across Europe, Asia and North America. Small series describe reduced relapse rates or stable disability scores; some show fewer inflammatory (gadolinium-enhancing) brain lesions over 6–12 months. MS is naturally variable, so separating stem-cell effects from disease fluctuation or concurrent disease-modifying drugs is difficult without controls. No trial has shown stem cells to be superior to established MS therapies; long-term data are sparse.
Depending on assessment, a Multiple Sclerosis protocol may draw on:
Indicative European costs are roughly €4,500–€7,500 per course, reflecting manufacturing, sterility testing, and often multiple doses. MS patients usually need MRI before and after, and intrathecal (spinal) delivery may require hospitalisation, raising the total. Established MS disease-modifying therapies cost roughly €800–€3,000 monthly via insurance and are proven — the stem-cell figure is indicative and unproven.
Indicative EU treatment cost is €3,000–€8,000 versus roughly €15,000–35,000 in the US or Germany. Build your real all-in total with the cost calculator, see the Multiple Sclerosis cost-by-country breakdown, or compare the best countries for Multiple Sclerosis →
Before booking, check safety & regulation, the recovery climate, 您是否可能是候选人, and which cell type fits Multiple Sclerosis.
We link primary regulators, registries and peer-reviewed research so you can verify everything yourself — plus the treating clinic's own materials.
Useful tools & guides: 我是候选人吗？ · 哪种细胞类型？ · Types of clinics & best countries · 成本计算器
由 StemCellAtlas 的编辑团队进行医学审查，与Kiian Nadiia, MD, PhD (Paediatric Neurologist · Medical Director, CSM Clinic Network · 12+ yrs in Autism Spectrum Disorders) 合作诊所 Stem Plus（索菲亚）的，根据 ISSCR、FDA 和 EMA 指南。 Educational information, not medical advice; figures indicative.
位于欧盟核心的 GMP 认证再生医学诊所——费用 3,000–8,000 欧元起，仅为美国或德国价格的一小部分。为来自 50 多个国家的国际患者提供个性化方案。
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