Question

What is the success rate of stem cell therapy for Complex Regional Pain Syndrome?

A reliable success rate for CRPS cell therapy is not established. Pain scores, function, medication use and return to activity are different endpoints, and uncontrolled clinic percentages are highly vulnerable to selection, placebo and loss-to-follow-up bias. The registered studies and their own prespecified endpoints are listed in the registry table on this page.

Medical review statusPending clinical sign-offLast evidence update: 2026-08-05Methodology and editorial standards
Clinical review team: Dr Kamelia Milcheva, Hematologist · Dr Vadym Uvarov, Board-Certified Physician · Hepatobiliary Surgeon · Candidate of Medical SciencesEditorial responsibility: StemCellAtlas research teamEducational information only. This page does not provide medical advice, diagnosis or a treatment recommendation.

What the evidence shows for Complex Regional Pain Syndrome

Evidence for CRPS cell therapy is very limited and does not establish efficacy. Preliminary or unpublished results, small samples and subjective outcomes cannot support a predictable pain or functional benefit. CRPS symptoms and placebo responses can vary substantially, making adequately blinded controls and long follow-up essential. No pooled response rate is published here. The registered studies and their own prespecified endpoints are listed in the registry table on this page.

Am I a candidate? → · Complex Regional Pain Syndrome: full overview → · Complex Regional Pain Syndrome cost → · Cost →

Evidence checked against ISSCR, FDA and EMA guidance. See our editorial standards. This is information, not medical advice. Educational information, not medical advice; figures indicative.

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