Infusion is outpatient or a brief inpatient stay, with 1–3 days acute recovery. Neurological recovery, where it occurs, is slow and incomplete, unfolding over weeks to months. Patients usually continue or resume disease-modifying therapy during and after. There is no period in which MS reverses; ongoing monitoring and symptom management remain standard.
Ninety-two registered trials and 14 recruiting studies investigate stem-cell therapy in MS, across Europe, Asia and North America. Small series describe reduced relapse rates or stable disability scores; some show fewer inflammatory (gadolinium-enhancing) brain lesions over 6–12 months. MS is naturally variable, so separating stem-cell effects from disease fluctuation or concurrent disease-modifying drugs is difficult without controls. No trial has shown stem cells to be superior to established MS therapies; long-term data are sparse.
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Revizuit medical de echipa editorială a StemCellAtlas cu Kiian Nadiia, MD, PhD (Paediatric Neurologist · Medical Director, CSM Clinic Network · 12+ yrs in Autism Spectrum Disorders) ale clinicii partenere Stem Plus (Sofia), în funcție de orientările ISSCR, FDA și EMA. Educational information, not medical advice; figures indicative.
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