Fibromyalgia is a disorder of central pain processing characterised by widespread musculoskeletal pain, fatigue, and sleep disturbance, often accompanied by cognitive difficulties ('fibro fog').
Fibromyalgia is a disorder of central pain processing characterised by widespread musculoskeletal pain, fatigue, and sleep disturbance, often accompanied by cognitive difficulties ('fibro fog'). No primary tissue damage is evident; instead, dysregulation of pain-signal amplification in the spinal cord and brain—low serotonin, elevated substance P, sensitised pain receptors—perpetuates the syndrome. The condition predominantly affects women and is often triggered by trauma, infection, or stress. Cell therapy exploration in fibromyalgia is nascent; placental MSCs and their secreted exosomes are being investigated for immunomodulatory properties (shifting immune response away from pro-inflammatory cytokine production) and for potential neuromodulation through delivery of anti-inflammatory molecules to the central nervous system. The hypothesis is that systemic cellular or exosome infusion might dampen the amplified pain state and restore normal sleep and mood regulation.
| التكلفة الموضحة · بلغاريا (الاتحاد الأوروبي) | €3,000–€8,000 |
|---|---|
| نطاق تكاليف السوق العالمي | €5,000–€25,000 (dvcstem.com) |
| أهم أنواع الخلايا المدروسة | MSCs from Amniotic Membrane, Exosomes |
| حالة الموافقة | تجريبي |
| التجارب المسجلة (ClinicalTrials.gov) | 1 |
For the clinic's own description, see our partner clinic Stem Plus.
Only 1 completed trial and 0 actively recruiting trials are registered specifically for fibromyalgia cell therapy, reflecting the early, exploratory stage of this application. That single published study involved placental MSC infusion in a small cohort (n≈20–30) and reported modest improvements in pain scores (average 20–30% reduction on visual analogue pain scale) and some improvement in fatigue severity. Biochemical markers of inflammation (IL-6, TNF-α) showed trending reductions. No control arm was present, and long-term follow-up was not reported.
Depending on assessment, a Fibromyalgia & Chronic Fatigue protocol may draw on:
Clinical applications of cell therapy for fibromyalgia are highly experimental and available in only a handful of private centres. Costs, where quoted, typically range from €4,000 to €7,000 for intravenous MSC infusion, though supportive testing (blood panels assessing cytokine profiles, baseline pain and fatigue questionnaires) may add €500–1,000. Insurance is not applicable because no standard treatment pathway exists; patients seeking this therapy are self-funding exploratory care.
Indicative EU treatment cost is €3,000–€8,000 versus roughly €15,000–35,000 in the US or Germany. Build your real all-in total with the cost calculator, see the Fibromyalgia & Chronic Fatigue cost-by-country breakdown, or compare the best countries for Fibromyalgia & Chronic Fatigue →
Before booking, check safety & regulation, the recovery climate, ما إذا كنت قد تكون مرشحاً, and which cell type fits Fibromyalgia & Chronic Fatigue.
أسئلة الألم العضلي الليفي ومتلازمة التعب المزمن الشاملة → · تفصيل تكاليف الألم العضلي الليفي ومتلازمة التعب المزمن →
We link primary regulators, registries and peer-reviewed research so you can verify everything yourself — plus the treating clinic's own materials.
Useful tools & guides: هل أنا مرشح؟ · أي نوع خلايا؟ · Types of clinics & best countries · حاسبة التكاليف
تم المراجعة الطبية بواسطة فريق التحرير StemCellAtlas مع Kiian Nadiia, MD, PhD (Paediatric Neurologist · Medical Director, CSM Clinic Network · 12+ yrs in Autism Spectrum Disorders) من عيادة الشريك Stem Plus (صوفيا)، وفقاً لـ ISSCR و FDA و EMA. Educational information, not medical advice; figures indicative.
طب تجديدي معتمد GMP في قلب الاتحاد الأوروبي — من 3,000 إلى 8,000 يورو، جزء بسيط من أسعار أمريكا أو ألمانيا. بروتوكولات مخصصة لمرضى من أكثر من 50 دولة.
مراجعة طبية مجانية